Peptide Research Protocols

PT-141 is a synthetic melanocortin receptor agonist primarily used for treating sexual dysfunction in both men and women. Unlike PDE5 inhibitors (Viagra/Cialis), it works centrally in the brain to increase sexual desire and arousal through melanocortin pathways rather than vascular mechanisms.

Melanotan 2 is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis, the production of melanin in the skin. Originally developed as a sunless tanning agent and potential skin cancer preventative, it also has aphrodisiac effects through melanocortin receptor activation.

DSIP is a naturally occurring nonapeptide that was first isolated from rabbit cerebral venous blood during slow-wave sleep. It acts as a neuromodulator and has been shown to increase sleep efficiency, reduce sleep latency, and provide neuroprotective effects through antioxidant mechanisms.

Kisspeptin is a hypothalamic neuropeptide that plays a critical role in regulating the reproductive axis by stimulating GnRH release. It is essential for puberty onset, fertility, and menstrual cycle regulation.

NAD+ is a critical coenzyme found in all living cells that plays essential roles in cellular energy metabolism, DNA repair, and signaling pathways. NAD+ levels decline with age.

SS-31 is a mitochondria-targeted tetrapeptide that binds to cardiolipin in the inner mitochondrial membrane. It improves mitochondrial function and reduces oxidative stress.

Dihexa is a synthetic peptide derived from angiotensin IV that was developed at Washington State University. It is a potent hepatocyte growth factor (HGF) activator and has shown remarkable cognitive enhancement in animal models of Alzheimer's disease.

GW-501516 is a PPARδ agonist originally developed for metabolic and cardiovascular diseases. It dramatically increases endurance by shifting muscle metabolism toward fatty acid oxidation. Note: This is technically not a peptide but a PPAR agonist compound.